Sleep as a longevity organ
Treat sleep as you would treat blood pressure or fitness: a system that either repairs you or ages you.
Short sleep and irregular sleep are...
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
Geroscience: Treating Aging Biology Itself
Geroscience starts from a simple claim that is still unusual in medicine: many of the diseases that dominate later life are not independent failures....
A plant-forward, protein-adequate diet — and not overeating
The eating pattern with the most consistent human data is not a named fad. It is a Mediterranean, or “green-Mediterranean,” plate: vegetables, fruit, legumes,...
Moderate Calories Without Malnutrition
Caloric restriction is the most replicated lifespan intervention in animals. Cut energy intake without starving the animal of vitamins, minerals, and protein, and yeast,...
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
Don’t Smoke, Limit Alcohol, and Avoid Opioid Dependence
In a study of more than 700,000 U.S. veterans, eight midlife habits predicted large differences in survival. Physical inactivity, smoking, and opioid use had...
Sleep 7–9 hours, regularly
Most adults need about seven to nine hours of sleep, on a schedule that barely moves from night to night. Duration gets the headlines....
A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity...
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
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