A Mediterranean-Style, Plant-Forward Diet with Enough Protein
Eating patterns built around vegetables, fruit, legumes, nuts, whole grains, olive oil, and fish—while keeping ultra-processed foods and excess red or processed meat low—consistently...
Geroscience: Treating Aging Biology Itself
Geroscience starts from a simple claim that is still unusual in medicine: many of the diseases that dominate later life are not independent failures....
MUST READ
Exercise — still the strongest single intervention
If you keep only one health habit, keep this one.
Cardiorespiratory fitness — usually measured as VO₂ max — and muscular strength predict how long...
Moderate Calories Without Malnutrition
Caloric restriction is the most replicated lifespan intervention in animals. Cut energy intake without starving the animal of vitamins, minerals, and protein, and yeast,...
Muscle mass and strength
Grip strength is a crude test. You squeeze a dynamometer as hard as you can. In a Lancet analysis of the PURE study it...
Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity Drug
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
Control blood pressure (often toward ~120 mm Hg systolic)
High blood pressure damages arteries for years before it causes a symptom. The SPRINT trial found that, in high-risk adults without diabetes, aiming for...
Sleep as a longevity organ
Treat sleep as you would treat blood pressure or fitness: a system that either repairs you or ages you.
Short sleep and irregular sleep are...
Regular heat exposure in the form of traditional Finnish-style sauna
Regular heat exposure in the form of traditional Finnish-style sauna stands out among passive interventions for its consistent links to lower cardiovascular mortality and...
A Mediterranean-Style, Plant-Forward Diet with Enough Protein
Eating patterns built around vegetables, fruit, legumes, nuts, whole grains, olive oil, and fish—while keeping ultra-processed foods and excess red or processed meat low—consistently...
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
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FOOD
A Mediterranean-Style, Plant-Forward Diet with Enough Protein
Eating patterns built around vegetables, fruit, legumes, nuts, whole grains, olive oil, and fish—while keeping ultra-processed foods and excess red or processed meat low—consistently...
Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity Drug
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
Social Connection, Purpose, and the Mortality Edge
Loneliness and social isolation are not merely unpleasant. Large-scale evidence shows they elevate the risk of earlier death on a scale that public-health researchers...
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Manage stress and support mental/emotional health
Chronic stress and poor mental health accelerate biological aging through inflammation, metabolic disruption, and behavioral pathways. A sense of purpose, positive relationships, mindfulness or...
Muscle mass and strength
Grip strength is a crude test. You squeeze a dynamometer as hard as you can. In a Lancet analysis of the PURE study it...
A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Senolytics and Clearing “Zombie” Cells
Aging tissues are not only worn out. Part of what they suffer is a form of pollution: a small population of cells that have...
Don’t Smoke, Limit Alcohol, and Avoid Opioid Dependence
In a study of more than 700,000 U.S. veterans, eight midlife habits predicted large differences in survival. Physical inactivity, smoking, and opioid use had...
HEALTH
Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity...
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
SCIENCE
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
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LATEST POSTS
A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Don’t Smoke, Limit Alcohol, and Avoid Opioid Dependence
In a study of more than 700,000 U.S. veterans, eight midlife habits predicted large differences in survival. Physical inactivity, smoking, and opioid use had...
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...