A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Geroscience: Treating Aging Biology Itself
Geroscience starts from a simple claim that is still unusual in medicine: many of the diseases that dominate later life are not independent failures....
Moderate Calories Without Malnutrition
Caloric restriction is the most replicated lifespan intervention in animals. Cut energy intake without starving the animal of vitamins, minerals, and protein, and yeast,...
Don’t Smoke, Limit Alcohol, and Avoid Opioid Dependence
In a study of more than 700,000 U.S. veterans, eight midlife habits predicted large differences in survival. Physical inactivity, smoking, and opioid use had...
Measuring Biological Age — and the First Steps Toward Cellular Reprogramming
Two linked discoveries are changing how aging is studied, and what it might mean to treat it. One is a better way to measure...
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
Control the “big four” killers early: lipids, blood pressure, glucose, tobacco
Most years of healthy life are still lost to atherosclerotic disease, cancer, metabolic disease and neurodegeneration. The tools that cut that list are not...
A plant-forward, protein-adequate diet — and not overeating
The eating pattern with the most consistent human data is not a named fad. It is a Mediterranean, or “green-Mediterranean,” plate: vegetables, fruit, legumes,...
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