Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity...
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
Social Connection, Purpose, and the Mortality Edge
Loneliness and social isolation are not merely unpleasant. Large-scale evidence shows they elevate the risk of earlier death on a scale that public-health researchers...
A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Muscle mass and strength
Grip strength is a crude test. You squeeze a dynamometer as hard as you can. In a Lancet analysis of the PURE study it...
Cardiorespiratory fitness (VO₂ max)
VO₂ max is the ceiling on how much oxygen your body can take in, deliver, and use when you are working as hard as...
Geroscience: Treating Aging Biology Itself
Geroscience starts from a simple claim that is still unusual in medicine: many of the diseases that dominate later life are not independent failures....
Moderate Calories Without Malnutrition
Caloric restriction is the most replicated lifespan intervention in animals. Cut energy intake without starving the animal of vitamins, minerals, and protein, and yeast,...
Measuring Biological Age — and the First Steps Toward Cellular Reprogramming
Two linked discoveries are changing how aging is studied, and what it might mean to treat it. One is a better way to measure...
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
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