Don’t Smoke, Limit Alcohol, and Avoid Opioid Dependence

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In a study of more than 700,000 U.S. veterans, eight midlife habits predicted large differences in survival. Physical inactivity, smoking, and opioid use had...

Measuring Biological Age — and the First Steps Toward Cellular Reprogramming

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Two linked discoveries are changing how aging is studied, and what it might mean to treat it. One is a better way to measure...

Nutrient-sensing drugs: rapamycin combinations and metformin

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Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...

Treat relationships, purpose, and mental load like vital signs.

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The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it. Northwestern’s SuperAging program...

Control the “big four” killers early: lipids, blood pressure, glucose, tobacco

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Most years of healthy life are still lost to atherosclerotic disease, cancer, metabolic disease and neurodegeneration. The tools that cut that list are not...

A plant-forward, protein-adequate diet — and not overeating

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The eating pattern with the most consistent human data is not a named fad. It is a Mediterranean, or “green-Mediterranean,” plate: vegetables, fruit, legumes,...

Sleep as a longevity organ

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Treat sleep as you would treat blood pressure or fitness: a system that either repairs you or ages you. Short sleep and irregular sleep are...
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