Measuring Biological Age — and the First Steps Toward Cellular Reprogramming
Two linked discoveries are changing how aging is studied, and what it might mean to treat it. One is a better way to measure...
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
Control the “big four” killers early: lipids, blood pressure, glucose, tobacco
Most years of healthy life are still lost to atherosclerotic disease, cancer, metabolic disease and neurodegeneration. The tools that cut that list are not...
A plant-forward, protein-adequate diet — and not overeating
The eating pattern with the most consistent human data is not a named fad. It is a Mediterranean, or “green-Mediterranean,” plate: vegetables, fruit, legumes,...
Sleep as a longevity organ
Treat sleep as you would treat blood pressure or fitness: a system that either repairs you or ages you.
Short sleep and irregular sleep are...
Exercise — still the strongest single intervention
If you keep only one health habit, keep this one.
Cardiorespiratory fitness — usually measured as VO₂ max — and muscular strength predict how long...



















