Nutrient-sensing drugs: rapamycin combinations and metformin

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Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...

Muscle mass and strength

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Grip strength is a crude test. You squeeze a dynamometer as hard as you can. In a Lancet analysis of the PURE study it...

Sleep 7–9 hours, regularly

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Most adults need about seven to nine hours of sleep, on a schedule that barely moves from night to night. Duration gets the headlines....

Control blood pressure (often toward ~120 mm Hg systolic)

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High blood pressure damages arteries for years before it causes a symptom. The SPRINT trial found that, in high-risk adults without diabetes, aiming for...
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