Treat relationships, purpose, and mental load like vital signs.
The people who keep a 50-year-old memory past 80 are not just lucky. They are unusually social, and their brains show it.
Northwestern’s SuperAging program...
Cardiorespiratory fitness (VO₂ max)
VO₂ max is the ceiling on how much oxygen your body can take in, deliver, and use when you are working as hard as...
A plant-forward, protein-adequate diet — and not overeating
The eating pattern with the most consistent human data is not a named fad. It is a Mediterranean, or “green-Mediterranean,” plate: vegetables, fruit, legumes,...
Moderate Calories Without Malnutrition
Caloric restriction is the most replicated lifespan intervention in animals. Cut energy intake without starving the animal of vitamins, minerals, and protein, and yeast,...
Geroscience: Treating Aging Biology Itself
Geroscience starts from a simple claim that is still unusual in medicine: many of the diseases that dominate later life are not independent failures....
Nutrient-sensing drugs: rapamycin combinations and metformin
Aging research has many promising leads and few that survive a hard test. The most consistent pharmacological lever in animals is still nutrient sensing:...
Muscle mass and strength
Grip strength is a crude test. You squeeze a dynamometer as hard as you can. In a Lancet analysis of the PURE study it...
A plant-rich eating pattern — not a miracle food
The diets that hold up over decades look alike. They are built from plants, use unsaturated fats, keep some fish and dairy, and stay...
Combined Resistance and Aerobic Exercise: The Closest Thing to a Longevity...
If there is a single behavioral intervention that most consistently moves the needle on how long and how well people live, it is structured...
Regular heat exposure in the form of traditional Finnish-style sauna
Regular heat exposure in the form of traditional Finnish-style sauna stands out among passive interventions for its consistent links to lower cardiovascular mortality and...
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